AI Overview
KAIST is an acronym for Korea Advanced Institute of Science and Technology. In 1981, the government merged KAIS and KIST to form KAIST, which kept the new name even after KIST became independent again.
KAIST has contributed to the industrialization of satellite technology and helped enhance the nation’s status. KAIST has also partnered with other universities, including NYU and Carnegie Mellon, to advance research and education.
Friday, January 3rd, 2025
KAIST Develops Foundational Technology to Revert Cancer Cells to Normal Cells
Author: KAIST Research Team
Source: KAIST
Publication Date: 23 December 2024
Link: KAIST Develops Foundational Technology to Revert Cancer Cells to Normal Cells
Stephan:
Here is what looks like it is going to be very good healthcare news. If cancer is an issue for you or someone you know or care for you might alert your oncologist about this research.
Despite the development of numerous cancer treatment technologies, the common goal of current cancer therapies is to eliminate cancer cells. This approach, however, faces fundamental limitations, including cancer cells developing resistance and returning, as well as severe side effects from the destruction of healthy cells.
KAIST (represented by President Kwang Hyung Lee) announced on the 20th of December that a research team led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering has developed a groundbreaking technology that can treat colon cancer by converting cancer cells into a state resembling normal colon cells without killing them, thus avoiding side effects.
The research team focused on the observation that during the oncogenesis process, normal cells regress along their differentiation trajectory. Building on this insight, they developed a technology to create a digital twin of the gene network associated with the differentiation trajectory of normal cells.
Through simulation analysis, the team systematically identified master molecular switches that induce normal cell differentiation. When these switches were applied to colon cancer cells, the cancer cells reverted to a normal-like state, a result confirmed through […]